genes, genomes and exons

What this neuron does

This neuron responds to genetics vocabulary, especially words like 'exons', 'introns', 'conserved' and 'HERVs' from gene and genome science. It is turned off by words like 'animal' and 'animals'. When turned up, the model's writing moved toward talk of mRNA and proteins.

Written by Claude from this neuron's activations and steering outputs. Confidence: high. Think it is wrong? Flag it (opens a prefilled issue on GitHub).

Fires most on

The text windows where this neuron's activation was highest. Amber marks positive activation; the outlined token is the peak. Hover a token for its strength.

1. #1 peak

   Model of probabilities (HMMgene) also can locate donor and acceptor sites.⏎- Splice variants: Alternative splicing, resulting in different combination of exons, has been found to occur⏎in the primary transcripts of at least 4

2. #2 peak

   - Search for consensus intron/exon sequences:⏎Analysis of a large number of mRNA genes has led to the identification of highly conserved consensus sequences⏎at the 5' and 3' ends of essentially all

3. #3 peak

   from the genome by a process known as recombinational deletion. They are thought to play a key role in evolution.⏎Human endogenous retroviruses (HERVs) are suspected of involvement in some autoimmune diseases, and cancers and in particular with

4. #4 peak

   )⏎which is converted into mRNA by the splicing out of internal sequences called "introns". The coding sequence in the mRNA⏎is derived from internal sequences called "ex

5. #5 peak

   with twice as much insulin or clotting factor as normal. At the very least, duplicate genes should be unnecessary and therefore vulnerable to being degraded into functionless pseudogenes as new mutations arise over time⏎An NIH-supported team offers a possible answer

6. #6 peak

   alternative burial rituals.⏎With a team of four counselors, psychologist Noé Kasali — who heads Bethesda's counseling program<|endoftext|>Human Endogenous Retroviruses (HERVs)⏎

Steering

Push this neuron up or down while the model writes, and watch what changes. The outputs were generated ahead of time, so nothing runs in your browser.

Most negative on

Where the activation went furthest below zero. Blue marks negative activation. Many neurons mean something different in each direction.

1. #1 peak

   may only apply to the chromosome 22 mutation.⏎“The authors should test the same hypothesis in other animal models of autism,” says Agustin Legido, professor of pediatrics and neuro

2. #2 peak

   ide-binding protein, suggesting that animals under calorie restriction can establish a structurally balanced architecture of gut microbiota that may

3. #3 peak

   from Harvard University and the Max Planck Institute of Neurobiology in Martinsried has now discovered individual neurons in the brain of zebrafish larvae that control the animals' swimming speed. Human movements are also

4. #4 peak

   these observations have led to the evolution of the Common Disease / Rare Variant hypothesis suggesting that the majority of the "missing heritability" in common and complex phenotypes is instead due to an individual's personal profile of rare or private DNA variants6

Which neurons in earlier layers feed this one, and which later ones it feeds. Amber links excite, blue links suppress; longer bars are stronger.

Activation histogram

How often this neuron fires at each strength. Almost always it does close to nothing (the tall bars in the middle); the snippets above are the rare moments it fired hard, amber for positive and blue for negative.

Logit lens

The words this neuron nudges the model toward (amber) or away from (blue) when it fires. A hint, not a label: many neurons work through later layers instead.